In sarcoidosis, which organ is commonly affected besides the lungs and brain?

• A. Liver
• B. Heart
• C. Kidneys
• D. Skin

Answer: (B)

In sarcoidosis, granulomas can form in multiple organs, not just the lungs. The heart is a well-recognized organ that can be involved, and this cardiac involvement is clinically important because it can cause rhythm problems, conduction blocks, and even heart failure. Granulomatous infiltration of the myocardium and the heart’s electrical conduction system explains symptoms like palpitations, syncope, or chest pain, and it can carry serious consequences if not identified and managed. So, among the organs listed, the heart is the best answer because cardiac involvement is a classic and clinically significant manifestation of sarcoidosis beyond the lungs and brain. While the liver and skin can also be affected, the heart is a key organ highlighted for its potential impact on prognosis and management.