Grey Turner's Sign is a sign of which condition?

• A. Retroperitoneal hemorrhage or pancreatitis
• B. Myocardial infarction
• C. Peptic ulcer disease
• D. Upper GI bleed

Answer: (A)

Grey Turner's sign is flank bruising caused by retroperitoneal bleeding. It most often appears with conditions that bleed into the retroperitoneal space, especially acute pancreatitis with hemorrhage or other retroperitoneal hemorrhages. Blood tracks along tissue planes to the flanks, producing ecchymosis that may take hours to days to become visible. This sign signals a significant, potentially life-threatening process.

It’s not typically associated with a myocardial infarction, which presents with chest pain and heart-related signs rather than flank bruising. It’s also not a classic finding of peptic ulcer disease or an upper GI bleed, which usually cause symptoms like abdominal pain, hematemesis, or melena rather than flank ecchymosis.